Publications (2010-present)


52. The M4 α-helix contributes differently to both the maturation and function of two prokaryotic pentameric ligand-gated ion channels
C.M. Hénault, P.F. Juranka, J.E. Baenziger
Journal of Biological Chemistry (2015) 290(41), 25118-25128

51. Nicotinic acetylcholine receptor-lipid interactions: mechanistic insight and biological function
J.E. Baenziger, C.M. Hénault, & J.P.D. Therien
BBA Biomembranes (2015) 1848(9), 1806–1817

50. Role of the fourth transmembrane α-helix in the allosteric modulation of pentameric ligand-gated ion channels
C.L. Carswell, C.M. Hénault, S. Murlidaran, J.P.D. Therien, P.F. Juranka, J.A. Surujballi, G. Brannigan & J.E. Baenziger
Structure (2015) 23(9), 1655-1664

49. Aromatic interactions at the M4-M1/M3 interface promote gating and influence the lipid sensitivities of pentameric ligand-gated ion channels
C.L. Carswell, J. Sun & J.E. Baenziger
J. Biol. Chem. (2015) 290, 24962507

48. The role of the M4 lipid-sensor in the folding, trafficking, and allosteric modulation of nicotinic acetylcholine receptors
C.M. Hénault, J. Sun, J.P.D. Therien, C.J.B. daCosta, C.L. Carswell, J.M. Labriola, P.J. Juranka & J.E. Baenziger
Neuropharmacology (2015) 96, 157-168

47. A novel mechanism for activating uncoupled nicotinic acetylcholine receptors
C.J.B. daCosta, L. Dey, J.P.D. Therien & J.E. Baenziger
Nat. Chem. Biol. (2013) 9, 701-707.
Highlighted in News and Views:  Andersen, O.S. Nat. Chem. Biol. (2013) 9, 667-668 

46. Gating of pentameric ligand-gated ion channels: structural insights and ambiguities
C.J.B. daCosta & J.E. Baenziger
Featured review in Structure (2013) 21, 1271-1283.

45. Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment
J.M. Labriola, A. Pandhare, M. Jansen, M.P. Blanton, P.-J. Corringer & J.E. Baenziger
Biol. Chem. (2013) 288, 11294-11303.

44. Molecular mechanisms of acetylcholine receptor-lipid interactions: from model membranes to human Biology
J.E. Baenziger & C.J.B. daCosta
Biophys. Rev. (2013) 5, 1-9.

43. Structural characterization and agonist binding to human α4β2 nicotinic receptors
C.J.B. daCosta, R.M. Sturgeon, A.K. Hamouda, M.P. Blanton & J.E. Baenziger
Biochem. Biophys. Res. Commun. (2011) 407, 456-460.

42. 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels
J.E. Baenziger & P.J. Corringer
Neuropharmacology (2011) 60, 116-125.

41. Phospholipase C activity affinity purifies with the Torpedo nicotinic acetylcholine receptor
J.M. Labriola, C.J.B. daCosta, S. Wang, D. Figeys, J.C. Smith, R.M. Sturgeon, & J.E. Baenziger
Biol. Chem. (2010) 285, 10337-10343.

40. Cations mediate interactions between the acetylcholine receptor and anionic lipids
R.M. Sturgeon & J.E. Baenziger
Biophys. J. (2010) 98, 989-998.

39. Preparation of reconstituted acetylcholine receptor membranes suitable for AFM imaging of lipid-protein interactions
Vuong, J.E. Baenziger & L.J. Johnston
Chem. Phys. Lipids  (2010) 163, 117-126.